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. Author manuscript; available in PMC: 2012 Jun 16.
Published in final edited form as: Bone Marrow Transplant. 2009 Nov 16;45(6):1068–1076. doi: 10.1038/bmt.2009.307

Table 3. Selection Criteria for Historical Controls.

  • First allogeneic transplant in 1997-2003

  • Age 18-60 years old

  • Disease: ALL, AML, CML, CLL, MDS, NHL and HD

  • HLA-id sib, 1-antigen mm related or matched unrelated donor

  • Bone marrow or peripheral blood graft

  • Conditioning:
    • -
      TBI – 10.0-14.4 Gy
    • -
      CY - 110-140 mg/kg

  • GVHD prophylaxis: MTX + CsA alone

  • Patient weight ≥ 40 kg at transplant

  • Platelets ≥ 20,000

  • No infection pretransplant

  • Karnofsky ≥70%

  • No clinically significant organ impairment

HLA-id sib indicates human leukocyte antigen identical sibling; 1-antigen mm, 1 antigen mismatch; TBI, total body irradiation; CY, cyclophosphamide; MTX, methotrexate; CSA, cyclosporine.