. Author manuscript; available in PMC: 2012 Dec 14.

Published in final edited form as: Nature. 2012 Apr 29;486(7402):266–270. doi: 10.1038/nature11114

Table 1. Top 20 candidate genes that cooperate with Kras^G12D to promote mPDA in KCTSB13 mice.

CISs were scored by tumor frequency with the narrowest 15K kernel spatial distribution of insertion sites. Chr: chromosome; N: number of tumors from which the CIS was found; I, total number of insertions of the CIS in the indicated tumors.

Gene	Chr	CIS Peak Location	CIS Height	N	I	Mutation in humans

Usp9x	X	12691773	158.1266	101	341
Pten	19	32872602	64.5204	61	96
Fndc3b	3	27562591	13.7096	55	67
Setd5	6	113057997	35.6176	52	71
Arfip1\|Fbxw7	3	84769635	21.6666	48	80	Yes⁵
Fam193a	5	34705809	24.3555	45	78
Ctnna1	18	35342868	20.2017	45	50
Magi1	6	93859940	13.3715	43	57
Mkln1	6	31414109	16.5263	41	53
Pum1	4	130288478	12.7948	41	46	Yes⁵
Farp1	14	121587858	9.407	39	47
Foxp1	6	98921646	19.5831	38	60
Arid1a	4	133268936	32.1628	38	47	Yes⁵
Acvr1b	15	101024934	31.1752	38	47	Yes¹⁵
Map4k3	17	81109860	13.2385	38	45	Yes⁵
Stag2	X	39535994	16.8613	37	48
Mll5	5	22982314	16.0001	37	43	Yes⁵
Atxn2\|Sh2b3	5	122267680	12.3174	37	41
Arhgap5	12	53644560	37.416	35	61
Gsk3b	16	38106972	21.79	35	43

Table 1. Top 20 candidate genes that cooperate with KrasG12D to promote mPDA in KCTSB13 mice.

Table 1. Top 20 candidate genes that cooperate with Kras^G12D to promote mPDA in KCTSB13 mice.