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Mean (SD) erythromycin breath test results
| Treatment (trial day) | AUC(0,60 min) (disintegrations min−1 min) n = 17 | Change from baseline n = 17 |
|---|---|---|
| Baseline (day −1) | 26 500 (7580) | – |
| 30 mg tolvaptan (day 1) | 26 700 (5580) | +3.5% |
| 200 mg ketoconazole (day 4) | 12 900 (3890)* | −49.4% |
| 30 mg tolvaptan + 200 mg ketoconazole (day 5) | 9 410 (3040)* | −63.3% |
P < 0.05 when compared with baseline.
