. 2011 Sep 20;21(10):1604–1615. doi: 10.1089/scd.2011.0390

Table 1.

Mean Dimension and Proportion Among 3 Bone Marrow Stromal Subpopulations After 30–35 Days of Culture in Normal and Myelodysplastic Syndrome Settings

Stroma	Stromal cell subpopulation^a	Percentages^b	DimensionsH/W (μm)^c
NBM	Round-shaped	4.3%±1.0%^d	17.6±5.9/15.0±3.3^d
	Spindle-shaped	21.7%±7.5%^d	135.2±49.7/18.8±7.5^d
	Large and flat	73.9%±8.2%^d	83.8±27.5/38.4±18.0^e
RC	Round-shaped	8.5%±1.2%^d	15.4±5.6/12.0±4.0^d
	Spindle-shaped	36.6%±2.3%^d	111.3±15.7/7.6±2.8^d
	Large and flat	54.8%±1.0%^d	39.2±38.7/20.4±10.7^e
RAEB	Round-shaped	16.7%±5.4%^d	16.1±2.1/13.4±2.6^d
	Spindle-shaped	24.8%±11.6%^e	164.7±96.5/25.4±11.4^e
	Large and flat	58.4%±13.2%^e	109.1±50.1/56.5±27.9^e

^{^a}

Assignment of subtypes was based on morphological characteristics.

^{^b}

Values represent mean percentages from 3 separate experiments (n=3)±SD from each group of cases.

^{^c}

The mean dimensions were evaluated on n_round-shaped=15, n_{spindle-shaped}=50, and n_large _flat=100 cells from each of the studied groups.

The statistical significance is ^dP<0.05; ^eP=0.05.

NBM, bone marrow-derived stroma from healthy volunteers; RC, stroma derived from refractory cytopenia patients; RAEB, stroma derived from refractory anemia with excess of blasts patients; SD, standard deviation.

The bold values highlight the main differences, in terms of distribution and size, between the three morphological types of stromal cells, in pathological settings compared to normal counterparts.