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Effect of JCM-16021 on colonic TPH expression in PI-IBS rats. Western immunoblots of TPH and the statistical analysis of protein level showed that JCM-16021 significantly decreased the colonic TPH expression in PI-IBS rats. Data are shown as mean ± S.E.M., n = 4 per group. # P < 0.05 versus normal rats, *P < 0.05 versus PI-IBS rats (t-test).
