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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: J Mol Cell Cardiol. 2011 Dec 1;52(3):773–782. doi: 10.1016/j.yjmcc.2011.11.012

Fig. 2.

Fig. 2

Mechanical parameters and Ca transients in isolated cardiomyocytes at baseline and under isoproterenol (100nM) stimulation. (A): Rates of shortening (+dL/dt), (B): Rates of relengthening (−dL/dt), (C): Shortening fraction (FS%), and (D): Cell length in isolated cardiomyocytes from wild type mice (PLN-WT, n = 5), PLN-KO (n = 4) and mutant PLN mice (PLN-R14Del, n = 6). Values are mean ± SEM. At least 27 to 80 cells were used for measurements of each parameter. *, p < 0.05 vs PLN-WT. (E): Ca transient amplitude (340/380 nm ratio) obtained from PLN-WT (n = 4), PLN-KO (n = 4) and PLN-R14Del (n = 4). Values are mean ± SEM. A minimum of 42–70 cells were studied. *, p < 0.05 vs PLN-WT. (F): Analysis of caffeine-induced Ca transients in PLN-WT (n = 7–9), PLN-KO (n = 4) and PLN-R14Del (n = 4) cardiomyocytes. 10 mmol/L caffeine was applied and caffeine induced amplitude was assessed. Values are mean ± SEM. A minimum of 30 cells were studied. *, p < 0.05 vs PLN-WT.