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The LuxI/LuxR–type quorum sensing in Gram-negative bacteria. The LuxI-like protein is an autoinducer synthase that catalyzes the formation of a specific acyl-homoserine lactone (AHL). The AHL freely diffuses through the cell membrane at high cell density. The LuxR is a transcriptional regulator that binds to the diffusing AHL and in turn activates the transcription of its target genes.
