Distribution of FADS Haplotypes in Human Populations
(A) The frequencies of the A (blue) and D (red) haplotypes on different continents are based on four SNPs genotyped in the HGDP populations. The remaining fractions represent mixes (gray) of haplotypes A and D. In Europe, data for the same four SNPs are included for all genotyped individuals in our five local population cohorts (EUROSPAN).
(B) Frequencies of A, D, and mixed haplotypes in HGDP populations in which at least ten individuals have been genotyped.
(C) Frequencies of the 28 SNPs on the FADS haplotypes for ten HapMap and 1,000 Genomes populations of African, European, and Asian ancestry. Phased SNP data for all chromosomes in a population are shown as colored rows. Each row consists of 28 elements, one for each SNP on the two main haplotypes. A SNP is colored blue if it is located on haplotype A and colored red if it is on haplotype D. Mixed haplotypes are represented by horizontal lines that contain both red and blue elements.