Table 3.
Kidney Disease-Targeted Scale Scores
| Scale | CHD-CHD (n=13) | CHD-DHD (n=10) | TRANSPLANT (n=20) | P for change among groups |
|---|---|---|---|---|
| Symptoms | ||||
| Baseline | 87.9 (9.1) | 80.7 (10.9) | 80.8 (11.5) | |
| 6 months | 87.5 (7.4) | 82.8 (9.3)b | 91.8 (8.7) | |
| adjusted mean change* (95% CI) | 1.2 (-3.3, 5.9) | 0.5 (-4.8, 18.4) | 8.8 (5.2, 12.4) | 0.01 |
| Effects of Kidney Dz | ||||
| Baseline | 69.5 (23.3) | 64.8 (28.3) | 72.4 (19.8) | |
| 6 months | 67.7 (18.7)b | 78.7 (16.3)bc | 95.1 (5.4) | |
| adjusted mean change* (95% CI) | -1.9 (-8.1, 4.3) | 10.9 (3.5, 18.4) | 18.6 (5.2, 12.4) | <0.001 |
| Burden of Kidney Dz | ||||
| Baseline | 64.9 (27.5) | 42.3 (29.3)a | 46.1 (24.2)a | |
| 6 months | 60.5 (28.2)b | 49.3 (9.1)bc | 76.5 (20.3) | |
| adjusted mean change* (95% CI) | 0.9 (-8.8, 4.3) | 4.2 (-7.2, 15.5) | 24.4 (16.8, 32.1) | 0.001 |
| WORK | ||||
| Baseline | 50.0 (45.6) | 50.0 (43.3) | 77.5 (37.9) | |
| 6 months | 46.1 (47.7)b | 45.0 (36.6)b | 85.0 (28.5) | |
| adjusted mean change* (95% CI) | -8.8 (-24.3,6.7) | -1.9 (-20.0, 16.2) | 13.9 (1.2, 26.6) | 0.07 |
| Cognitive Function | ||||
| Baseline | 89.7 (13.5) | 85.1 (10.9) | 79.6 (21.7) | |
| 6 months | 85.6 (15.1) | 91.3 (7.0) | 88.3 (14.9) | |
| adjusted mean change* (95% CI) | -1.1 (-8.7, 6.5) | 6.2 (-2.6, 15.1) | 2.4 (-3.6, 8.5) | 0.45 |
| SLEEP | ||||
| Baseline | 39.8 (13.4) | 45.0 (8.6) | 41.6 (11.4) | |
| 6 months | 42.3 (10.0) | 44.0 (15.5) | 36.2 (10.8) | |
| adjusted mean change* (95% CI) | 2.02 (-2.7,6.8) | -2.5 (-8.2, 3.1) | -5.3 (-9.0, -1,4) | 0.21 |
| Sexual Functioning | ||||
| Baseline | 85.5 (11.1) | 90.3 (17.4) | 83.1 (23.0) | |
| 6 months | 82.7 (14.1) | 87.5 (9.8) | 90.0 (21.6) | |
| adjusted mean change* (95% CI) | 6.5 (-7.1,20.2) | 4.3 (-10.7, 19.4) | 5.8 (-4.1, 15.8) | 0.97 |
Unless otherwise indicated, values are given as mean ± standard deviation.
Abbreviations:
CHD-CHD, remaining on conventional hemodialysis therapy; CHD-DHD, conventional hemodialysis to daily hemodialysis therapy; TRANSPLANT, received kidney transplant
*
adjusted mean change for baseline values (95% confidence intervals)
a
p<0.01 compared to CHD at visit 1
b
p<0.01 compared to TRANSPLANT at visit 2
c
p<0.01 compared to CHD at visit 2