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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Drug Alcohol Depend. 2012 Feb 13;123S1:S42–S51. doi: 10.1016/j.drugalcdep.2012.01.014

Figure 1. Power and Required Sample Size in Testing of Pleiotropy and Interaction.

Figure 1

Figure 1a. Power of Testing Pleiotropy When Adjusting for Nicotine Dependence: Effect Size by Prevalence of Comorbid Disorder (Response Variable)

Figure 1b. Power of Testing Interaction: Effect Size by Prevalence of Comorbid Disorder (Covariate)

Figure 1c. Required Sample Size for Testing Pleiotropy with 80% Power: Effect Size by Prevalence of Comorbid Disorder (Response Variable)

Figure 1d. Required Sample Size for Testing Interaction with 80% Power: Effect Size by Prevalence of Comorbid Disorder (Covariate)