TABLE 4.
Multivariate-adjusted odds ratios and 95% confidence intervals for associations between race/SES and pathologic Gleason sum, ECE, and SVI.
| Race/SES (quartiles from lowest to highest) | Path Gleason sum ≥ 7*
|
ECE
|
SVI
|
|||
|---|---|---|---|---|---|---|
| OR (95% CI) | P† | OR (95% CI) | P† | OR (95% CI) | P† | |
| Black v white | 1.08 (0.88–1.33) | 0.447 | 0.72 (0.57–0.92) | 0.007 | 1.16 (0.84–1.60) | 0.377 |
| Income | 0.017 | 0.211 | 0.291 | |||
| 1 | 1.0 | 1.0 | 1.0 | |||
| 2 | 1.02 (0.79–1.32) | 1.05 (0.79–1.41) | 0.75 (0.50–1.12) | |||
| 3 | 0.98 (0.76–1.27) | 0.91 (0.68–1.22) | 0.77 (0.52–1.15) | |||
| 4 | 0.73 (0.56–0.97) | 0.85 (0.62–1.16) | 0.77 (0.50–1.18) | |||
|
| ||||||
| Black v white | 1.10 (0.89–1.35) | 0.372 | 0.73 (0.57–0.93) | 0.010 | 1.17 (0.85–1.62) | 0.328 |
| Education | 0.259 | 0.322 | 0.551 | |||
| 1 | 1.0 | 1.0 | 1.0 | |||
| 2 | 1.09 (0.84–1.42) | 0.76 (0.57–1.03) | 0.72 (0.48–1.08) | |||
| 3 | 0.89 (0.69–1.15) | 0.89 (0.67–1.19) | 0.63 (0.41–0.97) | |||
| 4 | 0.91 (0.70–1.17) | 0.82 (0.61–1.10) | 0.90 (0.61–1.34) | |||
|
| ||||||
| Black v white | 1.07 (0.87–1.32) | 0.519 | 0.71 (0.56–0.90) | 0.005 | 1.17 (0.84–1.62) | 0.344 |
| Employment | 0.059 | 0.190 | 0.421 | |||
| 1 | 1.0 | 1.0 | 1.0 | |||
| 2 | 0.81 (0.62–1.04) | 0.74 (0.55–1.00) | 0.90 (0.60–1.36) | |||
| 3 | 0.77 (0.58–1.01) | 0.78 (0.57–1.07) | 1.04 (0.67–1.61) | |||
| 4 | 0.79 (0.60–1.04) | 0.83 (0.61–1.13) | 0.78 (0.50–1.21) | |||
|
| ||||||
| Black v white | 1.05 (0.85–1.30) | 0.624 | 0.73 (0.57–0.93) | 0.010 | 1.18 (0.85–1.63) | 0.327 |
| Poverty | 0.006 | 0.546 | 0.512 | |||
| 1 | 1.0 | 1.0 | 1.0 | |||
| 2 | 0.84 (0.64–1.09) | 1.15 (0.85–1.55) | 1.05 (0.70–1.59) | |||
| 3 | 0.78 (0.60–1.02) | 0.97 (0.71–1.32) | 0.92 (0.60–1.40) | |||
| 4 | 0.68 (0.52–0.90) | 0.92 (0.68–1.26) | 0.88 (0.57–1.35) | |||
NOTE. Each logistic regression model adjusted for age, year of surgery, SES measure, BMI, PSA, clinical stage, biopsy Gleason sum, race, and center. Analysis excluded missing values for pathologic Gleason sum (0.5% of total values).
ABBREVIATIONS. SES=socioeconomic status; ECE=extracapsular extension; SVI=seminal vesicle invasion; OR=odds ratio; CI=confidence interval
compared to men with pathologic Gleason sum<7 disease.
p-values for SES measures are for trends across SES quartiles.