TABLE 6.
Crude and multivariate-adjusted hazard ratios and 95% confidence intervals for associations between race/socioeconomic status and time to biochemical recurrence (n=888 events).
| Race/SES (quartiles from lowest to highest) | Crude Model
|
Model 1
|
Model 2
|
|||
|---|---|---|---|---|---|---|
| HR (95% CI) | P* | HR (95% CI) | P* | HR (95% CI) | P* | |
| Black v white | 1.20 (1.05–1.38) | 0.009 | 1.21 (1.04–1.40) | 0.016 | 1.19 (1.02–1.39) | 0.023 |
| Income | 0.001 | 0.264 | 0.795 | |||
| 1 | 1.0 | 1.0 | 1.0 | |||
| 2 | 0.96 (0.80–1.15) | 1.00 (0.83–1.20) | 1.01 (0.84–1.22) | |||
| 3 | 0.92 (0.77–1.10) | 0.97 (0.80–1.17) | 1.01 (0.84–1.22) | |||
| 4 | 0.74 (0.61–0.89) | 0.90 (0.73–1.10) | 0.98 (0.80–1.20) | |||
|
| ||||||
| Black v white | 1.20 (1.05–1.38) | 0.009 | 1.23 (1.05–1.42) | 0.008 | 1.22 (1.04–1.42) | 0.012 |
| Education | 0.592 | 0.564 | 0.101 | |||
| 1 | 1.0 | 1.0 | 1.0 | |||
| 2 | 1.05 (0.88–1.27) | 0.94 (0.78–1.14) | 1.08 (0.89–1.31) | |||
| 3 | 0.98 (0.81–1.18) | 1.00 (0.83–1.22) | 1.18 (0.97–1.43) | |||
| 4 | 0.97 (0.81–1.17) | 1.04 (0.86–1.26) | 1.15 (0.95–1.40) | |||
|
| ||||||
| Black v white | 1.20 (1.05–1.38) | 0.009 | 1.20 (1.03–1.39) | 0.022 | 1.19 (1.02–1.39) | 0.030 |
| Employment | 0.356 | 0.208 | 0.549 | |||
| 1 | 1.0 | 1.0 | 1.0 | |||
| 2 | 0.95 (0.79–1.14) | 0.92 (0.76–1.11) | 1.02 (0.84–1.23) | |||
| 3 | 0.93 (0.77–1.12) | 0.94 (0.77–1.15) | 0.96 (0.78–1.18) | |||
| 4 | 0.92 (0.77–1.11) | 0.87 (0.71–1.06) | 0.94 (0.77–1.16) | |||
|
| ||||||
| Black v white | 1.20 (1.05–1.38) | 0.009 | 1.19 (1.02–1.39) | 0.029 | 1.18 (1.01–1.37) | 0.040 |
| Poverty | 0.070 | 0.169 | 0.562 | |||
| 1 | 1.0 | 1.0 | 1.0 | |||
| 2 | 0.89 (0.74–1.06) | 0.88 (0.73–1.07) | 0.87 (0.72–1.06) | |||
| 3 | 0.95 (0.79–1.14) | 0.93 (0.76–1.13) | 0.97 (0.80–1.19) | |||
| 4 | 0.82 (0.68–0.99) | 0.86 (0.71–1.05) | 0.93 (0.76–1.13) | |||
NOTE. Model 1 is a Cox proportional hazards model adjusted for age, year of surgery, SES measure, BMI, PSA, clinical stage, biopsy Gleason sum, race, and center. Model 2 is a Cox proportional hazards model adjusted for age, year of surgery, SES measure, BMI, PSA, pathologic Gleason sum, race, center, PSM, ECE, and SVI.
ABBREVIATIONS. SES=socioeconomic status; HR=hazards ratio; CI=confidence interval.
p-values for SES measures are for trends across SES quartiles.