Table 1.
Demographic characteristics of the head and neck cases and controls
| Demographic characteristics | Cases | (%) | Controls | (%) |
|---|---|---|---|---|
| Total | 7002 | 8383 | ||
| Study | ||||
| France | 323 | 4.61 | 234 | 2.79 |
| New York Multicenter | 497 | 7.10 | 271 | 3.23 |
| Seattle, WA | 191 | 2.73 | 400 | 4.77 |
| North Carolina | 180 | 2.57 | 202 | 2.41 |
| Tampa, FL | 207 | 2.96 | 897 | 10.70 |
| Los Angeles, CA | 417 | 5.96 | 1005 | 11.99 |
| Puerto Rico | 350 | 5.00 | 521 | 6.21 |
| Latin America | 2191 | 31.29 | 1706 | 20.35 |
| IARC Multicenter | 983 | 14.04 | 1094 | 13.05 |
| Boston | 415 | 5.93 | 616 | 7.35 |
| US multicenter | 1114 | 15.91 | 1268 | 15.13 |
| Memorial Sloan-Kettering Cancer Center | 134 | 1.91 | 169 | 2.02 |
| Age | ||||
| <40 | 303 | 4.33 | 500 | 5.96 |
| 40_<45 | 403 | 5.76 | 597 | 7.12 |
| 45_<50 | 760 | 10.85 | 893 | 10.65 |
| 50_<55 | 996 | 14.22 | 1347 | 16.07 |
| 55_<60 | 1259 | 17.98 | 1455 | 17.36 |
| 60_<65 | 1117 | 15.95 | 1244 | 14.84 |
| 65_<70 | 950 | 13.57 | 1034 | 12.33 |
| 70_<75 | 707 | 10.10 | 724 | 8.64 |
| ≥75 | 507 | 7.24 | 589 | 7.03 |
| P for χ2test | <0.0001 | |||
| Sex | ||||
| Men | 5392 | 77.01 | 5791 | 69.08 |
| Women | 1610 | 22.99 | 2592 | 30.92 |
| P for χ2test | <0.0001 | |||
| Race/Ethnicity | ||||
| Nonhispanic white | 3922 | 56.01 | 5406 | 64.49 |
| Black | 557 | 7.95 | 659 | 7.86 |
| Hispanic/Latino | 156 | 2.23 | 359 | 4.28 |
| Asian/Pacific islanders | 37 | 0.53 | 72 | 0.86 |
| Others | 139 | 1.99 | 181 | 2.16 |
| Latin Americans* | 2191 | 31.29 | 1706 | 20.35 |
| P for χ2test | <0.0001 | |||
| Education | ||||
| None | 139 | 2.18 | 129 | 1.63 |
| <Junior high school | 2444 | 38.38 | 2073 | 26.17 |
| some high school | 1185 | 18.61 | 1117 | 14.10 |
| High school graduate | 728 | 11.43 | 960 | 12.12 |
| Vocational, some college | 1224 | 19.22 | 2042 | 25.78 |
| ≥College | 648 | 10.18 | 1601 | 20.21 |
| Missing | 634 | 461 | ||
| P for χ2test | <0.0001 | |||
| HNC subtype | ||||
| Oral cavity | 2028 | 0.29 | ||
| Pharynx | 2465 | 0.28 | ||
| Oral / pharynx not otherwise specified | 874 | 0.20 | ||
| Larynx | 1329 | 0.19 | ||
| Overlapping head and neck cancer | 306 | 0.04 |
*
: Information on ethnicity was not collected in the Latin America study. We organized subjects as “Latin American”. We adjusted for study center in all logistic regression models as a proxy variable for race/ethnicity because each center has an expected predominant ethnic group distribution.