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. Author manuscript; available in PMC: 2013 May 7.
Published in final edited form as: Phys Med Biol. 2012 Apr 13;57(9):2653–2666. doi: 10.1088/0031-9155/57/9/2653

Figure 1.

Figure 1

Diagram of method used to induce hyperthermia in small localized region of tumor and normal muscle. (a) Light from a 250 W halogen blub is transmitted into a 1cm diameter quartz rod. (b) A 3 mm fiber optic cable was attached to the end of the quartz rod. (c) The fiber optic cable was manufactured with a 90° bend in the end. This was placed flush to the surface of the mouse leg such that the cross section of the cable face was bisected by the tumor/normal muscle interface. This design produced an increase in tissue temperature of ~6° C, as demonstrated in bench experiments.