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Effect of PER1 overexpression and knockdown on SGLT1 promoter activity in CHO cells. Student’s t-test was used to compare promoter activity following overexpression of PER1 versus control and one-way ANOVA to compare effects of knockdown of PER1 versus control.
| Vector combination | Fold change in promoter activity vs. control | p-value | |
|---|---|---|---|
| Expression vector | Reporter vector | ||
| PER1 | WT-SGLT1luc | 0.89 | 0.24 |
| shPER1SeqA | WT-SGLT1luc | 1.46 | <0.05 |
| shPER1SeqB | WT-SGLT1luc | 1.47 | <0.05 |
