Table 1.

Clinical characteristics of women with the non-variant and variant KRAS alleles

	Variant KRAS allele	Non-variant (wt) KRAS allele	p-Value
Age	34.1	31.3	0.35
Stage IV disease	57%	56%	1
Years from diagnosis	9	6	0.31
Infertility	42%	18%	0.003
Irregular menses	28%	35%	0.34
Severe pain	42%	77%	0.001
Dysmenorrhea	42%	96%	0.0001
Dyspareunia	28%	69%	0.001

Subjects with the non-variant KRAS allele had severe pelvic pain, dyspareunia and dysmenorrhea more frequently than patients with the alternative KRAS allele. Subjects with the variant KRAS allele were more likely to be infertile. Mean age and severity were not different. n = 41 subjects with KRAS variant and 91 subjects with the WT allele.