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. 2012 May 23;32(21):7364–7372. doi: 10.1523/JNEUROSCI.0090-12.2012

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Copyright © 2012 the authors 0270-6474/12/327364-09$15.00/0

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Figure 6. — Modulation of input from layers 2/3 to layers 2/3 by stimulation of horizontal connections in layers 2/3 in V1. A, Graph showing the effects of modulation of inputs from layers 2/3 to layers 2/3 by stimulation of horizontal connections in layers 2/3 in V1. Conventions as in Figure 5D. The first three EPSCs are significantly reduced by modulation (p < 0.01 on a paired t test for the first two EPSCs, p < 0.05 for the third EPSC). Modulation has no effect on these amplitudes during either subsequent bath application of a Group II metabotropic glutamate receptor antagonist (p > 0.1 on a t test for all EPSCs) or in cells treated with GDPβS (p > 0.1 on a t test for all EPSCs). All amplitude values are normalized to the value measured in the control condition. B, Graph showing the effects of modulation on the paired-pulse ratio. Since both EPSCs are similarly decreased by modulation, the paired-pulse ratio is unchanged (p > 0.1 on a t test).