Table 1.
compd | LNCaP | PC-3 | ||||
---|---|---|---|---|---|---|
| ||||||
24 | 48 | 72 | 24 | 48 | 72 | |
rac-BEL | 13 | 5 | 9 | 34 | 26 | 14 |
2a | 10 | 5 | 5 | 19 | 23 | 14 |
2b | 9 | 5 | 7 | 32 | 15 | 16 |
rac-4 | 31 | 5 | 4 | 27 | 10 | 6 |
(S)-14a | 8 | 3 | 3 | 15 | 13 | 5 |
(R)-14b | 6 | 6 | 3 | 8 | 6 | 3 |
(S)-15 | 26 | 23 | 20 | 21 | 21 | 25 |
(S)-16 | 41 | 26 | 32 | 33 | 57 | 39 |
17 | 25 | 29 | 28 | 13 | 10 | 7 |
(S)-20 | 3 | 4 | 3 | 4 | 1 | 4 |
Data represent the calculated IC50 using data assessed 3–5 experiments ran in duplicate using separate passages of cells assessing alteration in MTT staining.