Table 3.
Plasma SAM concentrations in men and women by selected demographic, lifestyle and genetic factors
| Men (n = 204) | Women (n = 257) | |||||
|---|---|---|---|---|---|---|
| n | Geometric mean (95%CI) (nmol/L)a | Ptrend | n | Geometric mean (95%CI) (nmol/L)a | Ptrend | |
| Age at blood draw | ||||||
| <50 | 29 | 64.9 (59.1 – 71.3) | 0.17 | 43 | 59.7 (55.3 – 64.5) | 0.02 |
| 50 – 59 | 86 | 67.0 (63.5 – 70.8) | 126 | 58.2 (55.6 – 60.8) | ||
| 60 – 69 | 72 | 67.2 (63.3 – 71.3) | 58 | 68.0 (63.7 – 72.6) | ||
| ≥70 | 17 | 74.3 (65.8 – 84.1) | 30 | 63.1 (57.4 – 69.4) | ||
| BMI | ||||||
| <20 | 27 | 63.1 (57.2 – 69.5) | 0.02 | 41 | 59.0 (54.5 – 63.9) | 0.21 |
| 20 – <24 | 119 | 66.5 (63.5 – 69.6) | 147 | 60.7 (58.3 – 63.3) | ||
| 24 – <28 | 50 | 71.0 (66.2 – 76.3) | 58 | 63.3 (59.3 – 67.7) | ||
| ≥28 | 8 | 73.5 (61.5 – 87.8) | 11 | 62.0 (53.2 – 72.3) | ||
| Level of education | ||||||
| No formal school | 26 | 68.8 (62.0 – 76.4) | 0.26 | 96 | 60.2 (57.0 – 63.6) | 0.59 |
| Primary school | 94 | 68.2 (64.7 – 71.9) | 97 | 61.9 (58.8 – 65.2) | ||
| Secondary school | 58 | 67.0 (62.6 – 71.7) | 54 | 60.4 (56.3 – 64.8) | ||
| Some college or above | 26 | 63.6 (57.4 – 70.5) | 10 | 65.2 (55.5 – 76.6) | ||
| Smoking status | ||||||
| Never | 90 | 70.9 (67.2 – 74.8) | 0.004 | 243 | 61.2 (59.2 – 63.2) | 0.75 |
| Past | 53 | 67.2 (62.6 – 72.1) | 2 | 56.5 (39.4 – 80.9) | ||
| Current | 61 | 62.6 (58.8 – 66.7) | 12 | 60.0 (51.7 – 69.7) | ||
| Alcohol intake | ||||||
| None | 143 | 66.7 (63.9 – 69.6) | 0.32 | 239 | 60.8 (58.9 – 62.9) | 0.42 |
| <7 drinks/week | 45 | 68.3 (63.3 – 73.7) | 14 | 65.6 (57.2 – 75.2) | ||
| ≥7 drinks/week | 16 | 71.1 (62.6 – 80.7) | 4 | 62.1 (48.2 – 80.0) | ||
| MTHFR C677T | ||||||
| CC | 117 | 67.5 (64.4 – 70.8) | 0.82 | 139 | 59.9 (57.4 – 62.5) | 0.13 |
| CT | 69 | 67.7 (63.6 – 72.0) | 89 | 61.5 (58.3 – 64.9) | ||
| TT | 15 | 65.7 (57.6 – 75.0) | 22 | 65.7 (58.9 – 73.2) | ||
a
Adjusted for age at blood draw and serum creatinine concentrations.