. 2011 Jun;3(6):334–347. doi: 10.1002/emmm.201100141

Table 1.

Characteristics of the 37 patients with nonpolypoid and polypoid precancerous lesions included in the study (42 lesions).

Patient^a	Age	Sex	Colon segment involved^b	Maximum lesion diameter (mm)	Macroscopic appearance^c	Pit pattern^d	Microscopic appearance^e	Dysplasia^f	No. lesions present^g
Nonpolypoid
1^a^*	75	F	Tra	70	IIa-IIb	3S-3L	VA	high	7
1^b^*			Tra	20	IIa	3S-3L	VA	high
2^a^*	72	F	Cec	30	IIa	4	TA	low	9
2^b^*			Tra	20	IIa	3S-3L	TA	low
3	75	F	Tra	40	IIa-IIc	3S-3L	TA	high	1
4	73	F	Asc	40	IIa-IIc	2-3L	SA (mixed) ≠	high	1
5	44	M	HF	35	IIa	3S-3L	TA	low	2
6	79	F	Asc	20	IIa	4	TA	low	1
7	67	F	Asc	20	IIa	3L	TA	low	1
8	48	M	HF	15	IIa	3L	TA	low	1
9	69	F	Asc	40	IIa	3L	TVA	low	1
10	83	M	Asc	25	IIa	3L	TA	low	4
11	66	M	Cec	25	IIa	3L	TA	high	2
12	79	M	Asc	35	IIa-IIc	5N	TVA	high	2
13^a^*	54	F	Cec	45	IIa	3L	TVA	low	16
13^b^*			Asc	12	IIa	3L	TA	low
14	74	F	Cec	50	IIa	3L	TVA	low	1
15	62	F	Asc	15	IIa	3S-3L	SA (mixed)	low	1
16	52	F	Tra	15	IIa	2	SSA ≠	no dysplasia	1
17^a^*	54	F	Cec	50	IIa	2-3L	TA	high	2
17^b^*			Asc	20	IIa	2-3L	TA	low
18	72	M	Asc	25	IIa	3S-3L	TA	low	1
19^a^*	79	M	Asc	25	IIa	3L	VA	low	3
20	47	M	Asc	20-25	IIa-IIc	3S-3L	MVSP ≠	no dysplasia	3
21	66	M	Asc	12	IIa	3L	MVSP	no dysplasia	1
Polypoid
22	64	F	Asc	15	Ip	nr	TA	low	2
23	56	M	Asc	15	Ip	nr	TA	low	2
24	79	M	Asc	20	Ip	nr	TVA	low	3
25	27	M	Asc	15	Ip	nr	TVA	high	3
26	40	F	Sig	30	Ip	nr	TVA	low	51 §
27	83	M	Sig	12	Ip	nr	TVA	low	3
28	50	M	Sig	30	Ip	nr	TVA	high	3
29	74	F	Sig	20	Ip	nr	TVA	low	1
30	69	M	Rec	40	Ip	nr	TA	low	3
31	69	M	Sig	30	Ip	nr	TA	low	7
32	56	M	Sig	30	Ip	nr	TA	low	3
33	58	F	Des	20	Ip	nr	TA	low	3
34	52	F	Sig	30	Ip	nr	TA	low	3
35	69	F	Sig	15	Ip	nr	TVA	low	3
36	58	F	Asc	15	Ip	nr	TVA	low	1
19^b^*	79	M	Tra	30	Ip	nr	VA	low	3
37	73	M	Asc	30	Ip	nr	TVA	high	1

Two lesions were analyzed from patients marked with an asterisk.

Abbreviations: Cec, cecum; Asc, ascending colon; HF, hepatic flexure; Tra, transversum; Des, descending colon; Sig, sigma; Rec, rectum.

Classified according to the Paris Endoscopic Classification of Superficial Neoplastic Lesions (Paris Workshop Participants, 2003). All nonpolypoid lesions were slightly elevated (type IIa); a few also included a small region that was completely flat (IIb) or depressed (IIc).

Kudo classification of colonic crypt morphology (Kudo et al, 2001). Abbreviations: nr, Pit pattern not reported by the endoscopist.

Abbreviations: TA, tubular adenoma; TVA, tubulovillous adenoma; VA, villous adenoma; MVSP, microvescicular serrated polyp; SA, serrated adenoma; SSA, sessile serrated adenoma. ≠, Lesions carrying BRAFV600E mutation (valine to glutamate substitution at codon 600).

Highest degree of dysplasia in the lesion based on the WHO classification of tumors of the digestive system (Editorial and consensus conference in Lyon, France, November 6-9, 1999 [IARC]).

Total number of lesions noted during the study colonoscopy, including those used in the present study. §, Patient with suspected attenuated polyposis. The mutational analysis of the APC and MYH genes is currently not available.