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. 2011 Aug;3(8):480–494. doi: 10.1002/emmm.201100152

Figure 3. NCAM induces EOC cell migration by interacting with FGFR.

Figure 3

  1. SKOV3 cells transfected with empty vector (mock), with full-length NCAM or with NCAM-ΔFN2 were subjected to migration assays in the presence or absence of PD173074. A set of cells was co-transfected with dn-FGFR1 as indicated. Values are expressed in arbitrary units as fold changes over the migration of SKOV3-mock cells treated with vehicle.
  2. Parental SKOV3 cells were treated with Encamin-C or with a control scrambled peptide, either in the absence or in the presence of PD173074 or AG1478, followed by migration assay. Values are expressed in arbitrary units as fold changes over the migration of cells treated with the control peptide.
  3. C SKOV3 cells transfected with empty vector (mock) or with full-length NCAM were subjected to migration assays in the presence of the mAb 123C3, Eric-1 or anti-HA (as an isotype-matched control antibody). Values are expressed in arbitrary units as fold changes over the migration of untreated SKOV3-mock cells.