Skip to main content
. 2011 Nov;3(11):637–651. doi: 10.1002/emmm.201100172

Figure 4. Loss of RORγ leads to increased adipocyte formation in vivo.

Figure 4

  • A. Injection of SVF from different donor mice (as indicated) into the scapular subcutaneous region of C57Bl/6 mice. Fat pads were excised after 6 or 4 weeks of HFD feeding and stained as indicated.
  • B. Quantification of adipocyte differentiation in SVF transplants from wild-type and Rorγ−/− mice fed a high-fat diet for 4 weeks (n = 5).
  • C. Mean adipocyte size of Rorγ−/− and wild-type mice crossed into the ob/ob background or fed a high-fat diet for 8 weeks, insets are fat sections from representative samples of female DIO wild-type and Rorγ−/− mice (n = 7–10).
  • D,E. Adipocyte size distributions from subcutaneous and visceral adipose tissue of female DIO wild-type and Rorγ−/− mice (n = 7).
  • F. Mmp3 mRNA expression in visceral SVF of Rorγ−/− and wild-type mice on chow diet (n = 5). Values represent means ± SD, *p ≤ 0.05, **p ≤ 0.01 and ***p ≤ 0.001.