Repeated Measures Analysis of the Relationship between Food Insufficiency and Less Than 100% Adherence to Antiretroviral Therapy (63 cases, 113 outcomes, 1,264 interview months)

Variable	Univariable			Multivariablea,b
	O.R. [95% CI]	Z-statistic	p-value	O.R. [95% CI]	Z-statistic	p-value
Household food insufficiency (time-varying, any versus none)	2.0 [1.3, 3.1]	3.19	0.001	2.1 [1.4, 3.3]	3.34	0.0008
Female gender	1.6 [0.93, 2.8]	1.7	0.09
Age (years)	0.99 [0.96, 1.02]	-0.84	0.40
CD4 count at antiretroviral therapy start (per 20 cells/μL increase)	1.03 [0.99, 1.09]	1.35	0.18
Active tuberculosis	0.69 [0.41, 1.1]	-1.44	0.15
Body Mass Index (BMI) <18 (kg/m2)	0.84 [0.43, 1.6]	-0.51	0.61
Has spouse or partner	1.3 [0.75, 2.1]	0.87	0.39
Low education level (primary school or illiterate)	0.96 [0.42, 2.2]	-0.08	0.93
Unemployed	0.93 [0.52, 1.7]	-0.25	0.80
Lacks basic services (water, electricity and/or plumbing)	1.3 [0.76, 2.0]	0.88	0.38
Passed a day without eating due to poverty	2.0 [1.1, 3.3]	2.45	0.01
Physician-diagnosed drug abuse/dependence	0.84 [0.29, 2.4]	-0.32	0.75
Physician-diagnosed alcohol abuse/dependence	1.2 [0.65, 2.0]	0.48	0.63
Depression	1.4 [0.83, 2.4]	1.27	0.20
Good adherence self-efficacy	0.50 [0.28, 0.89]	-2.34	0.02	0.49 [0.28, 0.87]	-2.45	0.01
Social support score (per 5 point increase)	0.93 [0.88, 0.98]	-2.73	0.006	0.93 [0.88, 0.98]	-2.60	0.009
Quality of life score (per 5 point increase)	0.95 [0.85, 1.07]	-0.84	0.40
Perceived HIV stigma score (per 5 point increase)	1.03 [0.96, 1.10]	0.72	0.47

^aUnivariable models adjusted for day of treatment; multivariable models adjusted for day of treatment and study arm and variables shown.

^bAnalysis includes 1,261 interviews for 132 individuals with data for all covariates in model.