Table 2.
Summary of the studies which included N100 component
Study | Subjects | Paradigm | Results |
---|---|---|---|
[31] | 12 combat PTSD veterans 6 normal controls |
Four tones intensity paradigm | No difference in N1 amplitude |
[17] | 20 Israeli combat veterans with PTSD 20 without PTSD |
Visual oddball, trauma related non-related neutral stimuli |
Combat-related pictures elicited enhanced N1 amplitude in PTSD group. Prolonged N1 latencies and reaction times to target stimuli in PTSD patients. |
[56] | 16 medicated, 9 un-medicated PTSD 10 healthy veterans |
Auditory three-tone oddball | Longer N100 latencies in un-medicated PTSD patients compared to the medicated PTSD and healthy controls. |
[51] | 11 prisoners of war | Checkerboard reversal | Larger N75 amplitudes |
[39] | 11 PTSD survivors of a ship fire 9 psychiatric controls from the same ship |
Auditory word and non-word oddball | Increased N1 latency to standard tones; Larger amplitude to emotionally meaningful words. |
[25] | 13 females with sexual assault PTSD 16 healthy controls |
Auditory oddball | No difference in N100 amplitude and latency |
[28] | 17 civil PTSD 17 healthy controls |
Auditory oddball | No difference in N100 amplitude or latency |
[30] | 36 civil PTSD 20 healthy 10 depressed 8 alcoholics | 2000-Hz tone presented in increasing intensities | Increased N100 amplitudes |
[38] | 15 civil PTSD 15 controls |
Visual presentation of angry alternating with neutral faces | Larger N110 to the angry compared to the neutral faces in the control group. Smaller and later N100 in PTSD subjects. |
[35] | 10 civil PTSD 10 controls |
Auditory oddball | Larger N100 amplitude |
[42] | 19 PTSD 99 Alcohol dependence 16 personality disorder 25 anxiety or mood disorder | Visual presentation of happy, sad, and neutral faces | Larger N1 amplitudes to sad stimuli in frontotemporal leads in PTSD patients. |
[57] | 16 civil PTSD 16 schizophrenia 16 control subjects |
Auditory Oddball | No difference in N1 amplitude and latency |
[36] | 14 PTSD [mixed etiologies] 12 controls |
Auditory Oddball | No difference in N100 amplitude |