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. 2010 Jul;2(7):275–288. doi: 10.1002/emmm.201000081

Figure 3. Loss of VHL in CCRCC cells enhances EMCV replication.

Figure 3

  1. Loss of VHL in 786-O cells enhances EMCV replication. 786-O and 786-VHL cells were lysed and immunoblotted with anti-HA, anti-GLUT-1 and anti-α-Tubulin antibodies (left panel). Cells were challenged with EMCV (MOI = 0.01) and cumulative virus titre was evaluated at 3 h intervals post-infection (right graph). Two-way ANOVA was applied for statistical analysis between treatments and time points. * and *** denote p < 0.05 and p < 0.001, respectively.
  2. Loss of VHL in RCC4 cells enhances EMCV replication. RCC4-MOCK and RCC4-VHL cells were lysed and immunoblotted with anti-HA, anti-GLUT-1 and anti-α-Tubulin antibodies (left panel). Cells were challenged with EMCV (MOI = 0.01) and cumulative virus titre was evaluated at 3 h intervals post-infection (right graph). Two-way ANOVA was applied for statistical analysis between treatments and time points. * and *** denote p < 0.05 and p < 0.001, respectively.