Table 1.
Chr. Position |
Gene Position |
Allele | Genotype | HWE1 | ||||
---|---|---|---|---|---|---|---|---|
1 | 2 | 1/1 | 1/2 | 2/2 | p-Value | |||
rs1799971A/G2 | 151924380 | 355 | 282 | 40 | 125 | 32 | 4 | 0.41 |
rs510769 A/G3 | 151925602 | 1577 | 86 | 238 | 13 | 60 | 89 | 0.27 |
rs660756A/C | 151979108 | 54992 | 206 | 118 | 63 | 80 | 19 | 0.53 |
rs1918760 A/G | 152045410 | 121724 | 195 | 129 | 58 | 79 | 25 | 0.99 |
rs2281617C/T | 152050664 | 126978 | 280 | 44 | 121 | 38 | 3 | 1.0 |
rs1998220A/G | 152069596 | 145985 | 141 | 183 | 31 | 79 | 52 | 1.0 |
rs9371781A/C | 152115349 | 191764 | 226 | 98 | 78 | 70 | 14 | 0.94 |
Hardy Weinberg Equilibrium: p-Values assessed by Haploview software version 4.0
Significant associations with methamphetamine-induced pychosis,26 alcoholism,27 heroin addiction,28 completed suicide,29 and HPA axis activation36,37 (p<0.05).
Significant associations with vulnerability to heroin addiction,30 (p<0.05)