Table 1.

Allele and Genotype frequencies of the OPRM1 gene polymorphisms.

	Chr. Position	Gene Position	Allele		Genotype		HWE1
			1	2	1/1	1/2	2/2	p-Value
rs1799971A/G2	151924380	355	282	40	125	32	4	0.41
rs510769 A/G3	151925602	1577	86	238	13	60	89	0.27
rs660756A/C	151979108	54992	206	118	63	80	19	0.53
rs1918760 A/G	152045410	121724	195	129	58	79	25	0.99
rs2281617C/T	152050664	126978	280	44	121	38	3	1.0
rs1998220A/G	152069596	145985	141	183	31	79	52	1.0
rs9371781A/C	152115349	191764	226	98	78	70	14	0.94

¹Hardy Weinberg Equilibrium: p-Values assessed by Haploview software version 4.0

²Significant associations with methamphetamine-induced pychosis,26 alcoholism,27 heroin addiction,²⁸ completed suicide,²⁹ and HPA axis activation^36,37 (p<0.05).

³Significant associations with vulnerability to heroin addiction,³⁰ (p<0.05)