Population-averaged changes in eGFR after minimally invasive PN for patients given (gray line) and not given (black line) mannitol, adjusting for interval from surgery (modeled with splined terms), preoperative eGFR, American Society of Anesthesiologists score (1–2 vs 3–4), ischemia time, estimated blood loss, age, sex, year of surgery, and total nephrometry score (4–6, 7–9, 10–11). Dashed lines indicate 95% confidence intervals. Histogram shows number of eGFR measurements over time, excluding postoperative measurements taken within 2 days of surgery, which were recorded for all patients.