Table 10: Medical Advisory Secretariat Meta-Analysis of 6 Studies with Complete Data.
| Screening Modality by BIRADS Cut-off | No. studies/screens/tumors | Sensitivity (95%CI) | Specificity (95%CI) | |
|---|---|---|---|---|
| FM | ||||
| ≥3 | 3 / 2509/ 63 | 38.0 (26.0-51.0) | 94.4 (93.4-95.2) * | |
| ≥4 | 5 / 4272 / 115 | 28.0 (20.0-37.0) | 98.0 (97.5-98.4) * | |
| MRI | ||||
| ≥3 | 3 / 2509/ 63 | 81.0 (69.0-90.0) | 81.1 (79.5-82.6) | |
| ≥4 | 5 / 4272/ 115 | 77.0 (68.0-84.0) * | 95.9 (95.3-96.5) * | |
| MRI plus FM | ||||
| ≥3 | 3 / 2509/ 63 | 94.0 (85.0-98.0) | 77.2 (75.5-78.8) * | |
| ≥4 | 5 / 4272/ 115 | 84.0 (75.0-90.0)* | 95.2 (94.5-95.8) * | |
*
Significant statistical heterogeneity (chi-square p <0.10); MRI magnetic resonance imaging; FM film mammography.