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. 2009 Oct 1;9(15):1–62.

Table 14: GRADE Quality of Evidence for Interventions – Hydrophilic Acrylic Compared to All Other Materials.

Outcome Quality Assessment Summary of Findings
Design Quality Consistency Directness Other Effect Quality
PCO Cochrane systematic review Moderate* Consistent (5 studies) Direct

  • Varying follow-up but all >12 months. PCO methods varied so a “common scoring” system was used to enable summary statistics. Details not provided.

  • Some studies compared round with sharp edge IOLs.

 12.39 (9.82 to 14.95)
Mean difference (95% CI)		 Low†
BCDVA Cochrane systematic review Moderate* Consistent (4 studies) Direct

  • Some studies compared round with sharp edge IOLs.

 -0.09 (-0.13 to -0.06)
Mean difference (95% CI)		 Low†
Nd:YAG rate Cochrane systematic review Moderate* Consistent (4 studies) Direct

  • Some studies compared round with sharp edge IOLs.

 8.37 (3.74 to 20.36)
Odds ratio (95% CI)		 Low†
*

Downgraded due to study design (lack of details about randomization/blinding)

†

Downgraded due to mixing of round and sharp edge IOLs.