Table 29: Results from Roivio et al. (68).

Study/Year/Country	Type of Study	Patients	Outcomes	Results
Roivo et al., 2005 (68) Finland	Prospective cohort Investigate association between leisure time physical activity at midlife and subsequent development of dementia “Active” = participated in activity at least twice a week “Sedentary” = less than twice a week	Having been examined once at midlife, 1499 people (72.5%) aged 65–79 years participated in the reexamination in 1998 (mean follow-up 21 years).	Development of dementia Leisure time assess on questionnaire	Mean age at midlife exam was 50.6 years (range 39–64) Mean age at re-examination was 71.6 years (range 65–79) 115 people had dementia and 76 had Alzheimer’s disease Ascertained dementia cases from re-examination as well as hospital records for nonparticipants Comments: No follow-up measurements to assess changes occurring in physical activity