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. 2011 Nov 1;11(5):1–89.

Table 20: Corneal Stromal Haze after CXL.

Author, Year Haze Occurrence Finding Outcome
Caporossi A, 2010 (41) 36% (16/44) Temporary haze Resolved with steroids
Doors M, 2009 (52) 0% (0/29) No corneal haze detected  
Greenstein S, 2010 (94) 44 patients Haze dosimetry (Scheimpflug) and graded (slit lamp 0 to+4), haze greatest at 1 month, plateaued at 3 months, decreased between 3-and 12-months but still (p <.001) elevated at 12-months over baseline Absolute haze degree associated with poorer vision
El-Raggal T, 2009 (53) 100% (9/9) All eyes developed faint diffuse stromal haze Resolved at 1 month
Koller T, 2009 (45) 100% (21/21) All eyes showed stromal haze at 1 month with a demarcation line in deeper stroma in 18 patients At 6 months all corneas were clear except in 2 cases with discrete scarring in deep stroma
Lim L, 2011 (95) 7% (2/30) Permanent deep stromal scar near apical cone away from visual axis Not affecting vision at this time
Mazzotta C, 2008 (96) 11% (5/44) Transient corneal opacity similar to haze within first 3 months Resolved with topical steroids
Vinciguerra P, 2009 (42) 14% (4/28) Grade +1 haze (Hanna scale) Regressed after 1 month with topical steroids