Table 22: Change in Intraocular Pressure Following CXL*.
| Author, Year Patients | Observation Point | GAT-IOP Mean ± SD mm/HG | IOPcc - ORC Mean ± SD mm/HG | IOPg-ORC Mean ± SD mm/HG |
|---|---|---|---|---|
| Goldich Y, 2009 (101) | Baseline | 13.6 ± 2.06 | 10.2 ± 1.63 | 10.1 ± 1.66 |
| 1 week Postop | 16.7 ± 2.40 (P = .01) | 14.1 ± 2.21 (P < 0 .001) | 14.2 ± 2.73 (P < 0.001) | |
| 10 P | 1-month Postop | 16.5 ± 3.57 (P=04) | 13.2 ± 3.55 (P= 0.03) | 13.5 ± 3.12 (P= 0.01) |
| 3-months Postop | 15.3 ± 3.48 P=.19) | 11.6 ± 3.17 (P= 0.023) | 12.0 ± 1.25 (P= 0.01) | |
| 6-months Postop | 14.7 ± 2.87 (P=.21) | 11.2 ± 2.89 (P= 0.33) | 12.2 ± 1.14 (P= 0.16) | |
| Sedaghat M, 2010 (103) | Baseline | ND | 13.98 ± 2.9 | 10.47 ± 10.07 |
| 51 P | 6-months Postop | ND | 13.14 ± 2.8 (P= 0.027) | 10.07 ± 3.0 (P= 0.281) |
| Caporossi A, 2010 (41) | Baseline | 14.773 ± 1.696 (R, 11 to 18) | ND | ND |
| 44 P | 6-months Postop | 14.795 (P>.05) | ||
| 12-months Postop | 14.932 (P>.05) | |||
| Doors M, 2009 (52) | Baseline | 11.9 ± 3.5(R, 7 to 20)↑ | ND | ND |
| 29 P | 1,3,6 and 12-months Postop | NS (values not reported) | ||
| Raiskup-Wolf, F, 2008 (6) 130 P | Baseline change at 12-months Postop | 0.2 ± 1.4 (P>.05) | ND | ND |
| Wollensak G, 2003 (7) | Baseline | 13.6 ± 2.0 | ND | ND |
| 22 P | Last follow-up | 13.8 ± 2.5 (P = .612) | ||
| Kymionis G, 2010 (102) 55 P | Baseline | 9.95 ± 3.01 (R, 5 to 19) | ND | ND |
| 6-months Postop | 11.40 ± 2.89 (P<.001) (R, 7 to 19) | |||
| 12-months Postop | 11.35 ± 3.38 (P<.001) (R, 6 to 25) |
*
ND indicates not done; GAT, Goldman applanation tonometry; IOP, intraocular pressure; ORC, ocular response analyzer; P, patients; R, range; SD, standard deviation