Table 23: Impact of CXL on Endothelial Cell Density*.
| Author Year | Patients | Preop 2 cells/mm Mean ± SD | Postop 2 cells/mm Mean ± SD | Pre-Post Change | P-Value |
|---|---|---|---|---|---|
| Kymionis G, 2009 (99) | 15 | 2780 ± 197 | 2713 ± 116 | − 2.4% at 1 month | 0.14 |
| Caporossi A, 2010 (41) | 44 | 2451 ± 130 (R, 2092 to 3016) |
2444 R (nr) |
−2.0% at 12-months | > 0.05 |
| Doors M, 2009 (52) | 29 | 2701 ± 352 (R, 2071 to 3803) |
2703 ± 273 | unchanged | > 0.05 |
| Henriquez M, 2011 (44) | 10 | 2566 | 2464 at 6 months, 2484 at 12-months | − 3.3% at 12-months | > 0.05 |
| Leccisotti A, 2010 (46) | 51 | 2765 ± 176 | 2792 ± 146 | + at 6-months | > 0.05 |
| Vinciguerra P, 2009 (42) | 28 | 2651 ± 321 | 2598 ± 564 | −2.0% at 12-months | 0.13 |
| Wollensak G, 2003 (7) | 22 | NR | NR | unchanged | 0.45 |
| Vinciguerra P, 2009 (42) | 9 | 2555 ± 470 R(1515 to 2994) |
2120 ± 517 R(1547 to 2857) |
− 17% at 12-months | > 0.05 |
*
NR indicates not reported; R, range; SD, standard deviation