Table 1: Characteristics of meta-analyses included in systematic review by Heijenbrok-Kal, 2007*.
Study | Search Dates | Type of Stress | No of Studies (Patients) | CAD | Pooled Sensitivity | Pooled Specificity | Other Technologies Evaluated |
---|---|---|---|---|---|---|---|
O’Keefe et al., 1995 (16) | Database inception until Dec. 1993 | Ex SPECT Ad SPECT |
12 (2549) 8 (925) |
73% 80% |
90% 89% |
72% 83% |
Ex echo, Dob echo |
Fleischmann et al., 1998 (17) | Jan 1990 – Oct 1997 | Ex SPECT | 27 (3237) | 78% | 87% | 64% | Ex echo |
Kim et al., 2001 (18) | Jan 1997 – June 1999 | Ad SPECT Dip SPECT Dob SPECT |
9 (1207) 21 (1464) 14 (1066) |
80% 71% 66% |
90% 89% 82% |
75% 65% 75% |
Ad echo, Dip echo, Dob echo |
Imran et al., 2003 (19) | Jan 1986 – March 2001 | Mix SPECT | 13 (2922) | 71% | 81% | 65% | Dip echo |
Mowatt et al., 2004 (2) | Jan 1981 – Dec 2001 | Mix SPECT | 13 (2922) | 71% | 81% | 65% | Ex ECG |
Abbreviations: Ad, adenosine; CAD, coronary artery disease; Dip, dipyridamole; Dob, dobutamine; ECG, electrocardiogram; ECHO, echocardiography; Ex, Exercise; Mix, combination of stressors; NR, not reported.
Table adapted from Heijenbrok-Kal et al. (15)