Table 8: Summary incremental cost-effectiveness ratios across selected studies evaluating SPECT.

Study	Comparator	Outcome of interest	Reported as cost-effective?	ICER
Sharples et al., 2007	MRI	Cost per QALY	Yes	Dominant
Bedetti et al., 2008	Stress ECHO	Cost per correct diagnosis	No	Dominated
Garber et al., 1999	Stress ECHO	Cost per QALY	No	USD (1996) $78,444
Hayashino et al., 2004	Stress ECHO	Cost per QALY	No	Dominated
Hernandez et al., 2007	Stress ECHO	Cost per QALY	No	Dominated
Kuntz et al., 1999	Stress ECHO	Cost per QALY	No	USD (1996) $62,800
Lee et al., 2002	Stress ECHO	Cost per QALY	Yes	Not reported*
Sharples et al., 2007	Stress ECHO	Cost per QALY	Yes	Less costly, same QALYs
Shaw et al., 2066	Stress ECHO	Cost per LYS	No	USD (2003) $72,187

Abbreviation: ND = Not defined

^*SPECT was cost-effective when the probability of CAD was >=30%. Stress ECHO was cost-effective when the probability of CAD was <=20%.