Table 10: Design of Studies Included in the Evidence-Based Analysis.

Design	Comparators in Parent RCT if Subset Analysis
Retrospective subset analysis of RCT (Malmo Ocular Hypertension Study [MOHS]) (22) 2005 Sweden	Timolol vs. placebo
Retrospective analysis of RCT (Bergea et al.) (23) 1999 Sweden	Surgery vs. pilocarpine
Observational (unclear if prospective or retrospective) (Jonas et al.) (25) 2007 Germany	NA
Retrospective chart review (Choi et al.) (24) 2007 Korea	NA
Retrospective subset analysis of an RCT (Advanced Glaucoma Intervention Study [AGIS]) (15) 2008 US	2 sequences of glaucoma surgery
Retrospective subset analysis of an observational study (Diagnostic Innovations in Glaucoma Study [DIGS]) (16) 2008 US	Diagnostic and monitoring techniques
Retrospective subset analysis of an RCT (Early Manifest Glaucoma Trial [EMGT]) (26) 2007 Sweden/US	Surgery plus betaxolol vs. no surgery/betaxolol

RCT refers to randomized controlled trial