Table 3: Characteristics of meta-analyses included in Heijenbrok-Kal et al., 2007 systematic review^*.

Study	Search Dates	Type of Stress ECHO	No of Studies Included	Patient Characteristics	% Diagnosed With CAD on CA	Pooled Sensitivity	Pooled Specificity	Other Technologies Evaluated
O’Keefe et al., 1995 (17)	Up until Dec 1993	Ex ECHO Dob ECHO	12 (913 patients) 14 (1049 patients)	NR	72 69	81 81	89 83	Ex SPECT, Ad SPECT
Fleischmann et al., 1998 (18)	Jan 1990 - Oct 1997	Ex ECHO	24 (2637 patients)	mean age 59 yrs 69% men 20% previous MI	66	85	77	Ex SPECT
Picano et al., 2000 (19)	1985 -1998	Dip ECHO Dob ECHO	38 (2856 patients) 59 (5082 patients)	26% previous MI 26% previous MI	65 73	73 81	91 83	None
de Albuquerque Fonseca et al., 2001 (20)	1997-2000	Dip ECHO Ex ECHO	8 (533 patients) 8 (533 patients)	NR	74 74	72 79	92 82	None
Kim et al, 2001 (21)	Jan 1997 - June 1999	Ad ECHO	6 (516 patients)	mean age 65 yrs 71% men 31% previous MI	73	72	91	Ad SPECT, Dip SPECT, Dob SEPCT, EBCT
		Dip ECHO	20 (1835 patients)	mean age 56 yrs 72% men 15% previous MI	67	70	93
		Dob ECHO	40 (4097 patients)	mean age 59 yrs 66% men 26% previous MI	70	80	84
Imran et al., 2003 (22)	1986 - March 2001	Dip ECHO	10 (651 patients)	NR	67	70	90	Mix SPECT
Noguchi et al., 2005 (23)	1981 - Dec 2001	Ex ECHO	44 (3714 patients)	mean age 57 yrs 73% men 11% previous MI	70	83	84	None
		Ad ECHO	11 (678 patients)	mean age 64 yrs 76% men 21% previous MI	77	68	81
		Dob ECHO	80 (7914 patients)	mean age 59 yrs 70% men 13% previous MI	69	80	85
		Dip ECHO	40 (3466 patients)	mean age 56 yrs 73% men 9% previous MI	70	71	92

Ad refers to adenosine; CAD, coronary artery disease; Dip, dipyridamole; Dob, dobutamine; ECHO, echocardiography; Ex, Exercise; Mix, combination of stressors; NR, not reported.

^*Table adapted from Heijenbrok-Kal et al. (1)