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. 2010 Dec 1;10(22):1–28.

Table 6: Skin Grafting: Outcomes Reported by Vuerstaek et al. (7).

Time to complete healing Day (95% CI) Healed within 43 days Wound bed preparation Day (95% CI) Recurrence after 1 year follow-up N (%) Median percentage skin graft survival (SD) Quality of Life Pain scores
NPWT: 29 (25.5-32.5)
Control: 45 (36.2-53.8)
P = .0001
NPWT: 90%
Control: 48%
NPWT: 7 (5.7-8.3)
Control: 17 (10-24)
P = .005
NPWT: 12 (52)
Control: 10 (42)
P = .47
NPWT: 83 (14)
Control: 70 (31)
P = .011
Significant increase at the end of therapy in both groups Significant decrease at the end of therapy in both groups
HR = 3.2
(95% CI 1.7-6.2)
HR = 2.4
(95% CI 1.2-4.7)
1st week:
Lower in NPWT
(P = .031)
2nd week
No difference Follow-up
No difference
1st week:
No difference
1st week:
Lower in NPWT

NPWT, Negative pressure wound therapy; HR, Hazard Ratio