Table 3: Summary of weighted mean sensitivity, specificity, positive predictive value, and negative predictive value for predicting hibernating myocardium from Schinkel et al.^*.

Outcome	No. Studies	N	Sensitivity (%)	Specificity (%)	PPV (%)	NPV(%)
Positron Emission Tomography
Regional Function	24	756	92	63	74	87
Global Function	3	253	83	64	68	80
Dobutamine Echocardiography
Regional Function	41	1,421	80	78	75	83
Global Function	6	287	57	73	63	68
SPECT: Thallium-201
Regional Function	40	1,119	87	54	67	79
Global Function	5	235	84	53	76	64
SPECT: Technetium-99m
Regional Function	25	721	83	65	74	76
Global Function	2	98	84	68	74	80
Cardiac MRI: Resting MRI (End-Diastolic Wall thickness)
Regional Function	3	100	95	41	56	92
Global Function
Cardiac MRI: Dobutamine MRI
Regional Function	9	272	74	82	78	78
Global Function
Cardiac MRI: Contrast Enhanced MRI
Regional Function	5	178	84	63	72	78
Global Function

^*Cardiac MRI refers to cardiac magnetic resonance imaging; N, sample size; no., number; NPV, negative predictive value; PPV, positive predictive value; revasc., revascularization; SPECT, single photon emission computed tomography

Source: Schinkel AF, Bax JJ, Poldermans D, Elhendy A, Ferrari R, Rahimtoola SH. Hibernating myocardium: diagnosis and patient outcomes. Curr Probl Cardiol 2007; 32(7):375-410. Mortality rates were compared between patients with viable myocardium who were revascularized or treated with medical therapy and patients without viable myocardium who were revascularized or treated with medical therapy (Table 3). Mortality rates were pooled and annualized for ten studies that used PET for the assessment of viability. Patients with viable myocardium who were revascularized experienced the lowest annualized mortality rate (4%) compared with the highest rate (17%) among patients with viable myocardium treated with medical therapy. Similar trends were observed for the other diagnostic imaging modalities.