Table 11: Pooled estimates of sensitivity and specificity by subgroup.
| Subgroup | Sensitivity (%) | Specificity (%) | AUC | ||
|---|---|---|---|---|---|
| Pooled estimate (95% CI) | Range | Pooled estimate (95% CI) | Range | ||
| Mean preoperative LVEF | |||||
| LVEF < 40% | 92.0 (86.5 – 97.5) | 75 – 100 | 73.0 (59.7 – 86.2) | 33 – 92 | 0.898 |
| LVEF ≥ 40% | 91.4 (87.2 – 95.6) | 76 – 100 | 70.9 (59.9 – 81.8) | 35 – 91 | 0.909 |
| Method of Functional Recovery Assessment | |||||
| ECHO | 91.0 (86.4 – 95.6) | 76 – 100 | 69.8 (58.2 – 81.4) | 33 – 92 | 0.892 |
| cardiac MRI | 92.9 (87.4 – 98.3) | 86 – 100 | 80.9 (67.8 – 94.0) | 73 – 87 | 0.945 |
| MUGA* | 84.5 (57.1 – 100.0) | 83 | 92.1 (72.9 – 100.0) | 91 | Cannot calculate |
| Ventriculography | 91.1 (80.1 – 100.0) | 89 – 92 | 51.3 (24.6 – 78.0) | 35 – 68 | 0.798 |
| Type of Radiotracer | |||||
| PET perfusion tracer | 89.9 (83.5 – 96.4) | 75 – 100 | 78.3 (66.3 – 90.2) | 50 – 92 | 0.926 |
| SPECT perfusion tracer | 87.2 (78.0 – 96.4) | 76 – 92 | 67.1 (48.3 – 85.9) | 35 – 86 | 0.864 |
| FDG alone | 94.5 (91.0 – 98.0) | 79 – 100 | 66.8 (53.2 – 80.3) | 33 – 90 | 0.926 |
| Type of Segment | |||||
| Revascularized segments | 93.0 (89.8 – 96.2) | 69 – 100 | 70.9 (61.2 – 80.5) | 33 – 94 | 0.915 |
| All dysfunctional segments | 88.1 (80.0 – 96.3) | 76 – 100 | 81.0 (69.2 – 92.8) | 50 – 92 | 0.903 |
| Unit of Analysis | |||||
| Patient | 91.1 (84.8 – 97.4) | 75 – 100 | 68.6 (53.3 – 83.9) | 50 – 91 | 0.892 |
| Vascular territories | 93.9 (86.4 – 100.0) | 92 – 100 | 73.2 (52.7 – 93.7) | 35 – 92 | 0.864 |
| Segment | 89.9 (85.5 – 94.2) | 76 – 99 | 72.7 (62.7 – 82.6) | 33 – 90 | 0.886 |
AUC refers to area under the curve; cardiac MRI; cardiac magnetic resonance imaging; ECHO, echocardiography; FDG, F-18-fluorodeoxyglucose; LVEF, left ventricular ejection fraction; MUGA, multigated acquisition scan; PET, positron emission tomography; SPECT, single photon emission computed tomography
*
There is only 1 study in the MUGA subgroup, so a range is not available.