Table 20: Study characteristics of prognostic studies.
| Author, year | Study design | Patient population | Sample size |
Mean follow-up (months) |
Technique (tracer) |
Outcomes | Viability criteria |
|---|---|---|---|---|---|---|---|
| Marwick et al., 1999 (62) |
Prospective observational study | Patients with LV dysfunction who underwent CABG | 63 | 11±11 months (QOL) 6±4 (exercise testing) |
Rb-82 / FDG PET | Exercise capacity, functional class, quality of life, and mortality/MI | Segments that demonstrate ischemic (<15% relative reduction of activity after stress) or hibernating (FDG activity within 2 standard deviations (>70%) of normal within a perfusion defect were defined as viable |
| Marwick et al., 1992 (49) |
Prospective observational study | Patients with previous MI with clinical uncertainty about presence of viable myocardium | 23 | 22±14 wk | Rb-82 / FDG PET | Exercise capacity, functional class, and regional/global functional recovery | Avid FDG uptake despite hypoperfusion at rest |
FDG refers to F-18-fluorodeoxyglucose; LV, left ventricle; MI, myocardial infarction; QOL, quality of life; Rb, rubidium; SPECT, single-photon emission computed tomography; Tl, thallium; wk, week