Table 1. Overview of agents used for the treatment of TK6 cell cultures.
Agents | IARC | Category | Concentration (µM) | ||
High | Medium | Low | |||
Formaldehyde*,1,2 | 1 | Aldehyde | 100 | 10 | 1 |
Styrene**,1 | 2B | Aromatic hydrocarbon | 5000 | 500 | 50 |
Styrene 7,8-oxide*,1 | 2A | Aromatic hydrocarbon | 500 | 50 | 5 |
Benzene**,1 | 1 | Aromatic hydrocarbon | 100 | 10 | 1 |
Hydroquinone*,1 | 3 | Aromatic hydrocarbon | 0.5 | 0.05 | 0.005 |
Mitomycin C*,2 | 2B | Cytostaticum | 0.5 | 0.05 | 0.005 |
Ethylenedibromide**,1,2 | 2A | Organobromide | 1000 | 100 | 10 |
Epichlorohydrin*,1 | 2A | Organochloride | 500 | 50 | 5 |
Acrylamide**,1 | 2A | Amide | 500 | 50 | 5 |
Trichloroethylene**,1 | 2A | Chlorinated hydrocarbon | 5000 | 500 | 50 |
Carbontetrachloride**,1 | 2B | Chlorinated hydrocarbon | 1000 | 100 | 10 |
Cyclophosphamide**,1 | 1 | Cytostaticum | 50 | 5 | 0.5 |
Benzo[a]fluoranthene**,1 | 2B | Poly aromatic hydrocarbon | 500 | 50 | 5 |
Benzo[a]pyrene**,1 | 1 | Poly aromatic hydrocarbon | 500 | 50 | 5 |
Benz[a]anthracene**,1 | 2B | Poly aromatic hydrocarbon | 500 | 50 | 5 |
Direct acting agent; **Indirect acting agent,
1: DNA adduct forming agent; 2: DNA Cross linking agent.