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. 2012 Jun 18;7(6):e39205. doi: 10.1371/journal.pone.0039205

Table 1. Overview of agents used for the treatment of TK6 cell cultures.

Agents IARC Category Concentration (µM)
High Medium Low
Formaldehyde*,1,2 1 Aldehyde 100 10 1
Styrene**,1 2B Aromatic hydrocarbon 5000 500 50
Styrene 7,8-oxide*,1 2A Aromatic hydrocarbon 500 50 5
Benzene**,1 1 Aromatic hydrocarbon 100 10 1
Hydroquinone*,1 3 Aromatic hydrocarbon 0.5 0.05 0.005
Mitomycin C*,2 2B Cytostaticum 0.5 0.05 0.005
Ethylenedibromide**,1,2 2A Organobromide 1000 100 10
Epichlorohydrin*,1 2A Organochloride 500 50 5
Acrylamide**,1 2A Amide 500 50 5
Trichloroethylene**,1 2A Chlorinated hydrocarbon 5000 500 50
Carbontetrachloride**,1 2B Chlorinated hydrocarbon 1000 100 10
Cyclophosphamide**,1 1 Cytostaticum 50 5 0.5
Benzo[a]fluoranthene**,1 2B Poly aromatic hydrocarbon 500 50 5
Benzo[a]pyrene**,1 1 Poly aromatic hydrocarbon 500 50 5
Benz[a]anthracene**,1 2B Poly aromatic hydrocarbon 500 50 5
*

Direct acting agent; **Indirect acting agent,

1: DNA adduct forming agent; 2: DNA Cross linking agent.