Table 3. Functional classification of affected genes at medium dose.
GO ID | Go Processes | Carcinogens* | |||||
BA | BZ | CCL | CP | EPI | TCE | ||
GO:0019885 | Antigen processing and presentation of endogenous peptide antigen via MHC class I | P | P | O | P | P | P |
GO:0001711 | Endodermal cell fate commitment | P | O | P | O | P | P |
GO:0006450 | Regulation of translational fidelity | P | P | P | O | P | P |
GO:0030858 | Positive regulation of epithelial cell differentiation | P | O | P | O | P | P |
Functional classification of significantly affected genes by exposure to carcinogens at medium dose into Gene Ontology (GO) categories was performed. GO categories that were affected by 4 or more carcinogens per chemical dose are listed. A list of all GO categories affected per chemical per dose is given in the supplementary Table S2.
Carcinogens [BA:Benz[a]anthracene; BZ:Benzene; CCL:Carbontetrachloride; CP:Cyclophosphamide; EPI:Epichlorohydrin; TCE:Trichloroethylene].