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A, Presence of B220−IgGhigh basophil population (boxed) in the bone marrow of gp96 KO mice. B, Intracellular stain demonstrated an efficient deletion of gp96 in bone marrow cells of Hsp90b1floxRosa26ERcre (KO) mice by TAM. C, Both WT and gp96 KO B220−IgGhigh basophils express FcεRI (open histogram indicates gp96 or FcεRI; shaded histogram, isotype control).
