Table 2. Brain regions exhibiting significantly increased functional connectivity with the cerebellum in adults with major depression.

Seed Region	Target Area	Side	BA	MNI(x, y, z)			Cluster size	t-score	Mean z(r) (MDD/HC)
L Lobule VI**	Temporal Pole	R	21	42	3	−30	80	5.36	0.09/−0.05
	Middle Frontal Cortex	L	10	−33	54	21	192	4.97	−0.02/−0.14
R Lobule VI**	Temporal Pole	R	38	42	3	−33	91	4.43	0.11/−0.06
L Crus I**	Lobule VIII	L		−39	−39	−48	92	4.66	−0.04/−0.11
R Crus I*	Inferior Temporal Gyrus	R		12	−66	−45	1477	5.26	−0.32/−0.85
L Crus II*	Lobule VIIb/VIII/IX	L/R	38	42	6	−30	18	6.15	0.13/−0.09
	Temporal Pole	R	38	−36	12	−15	16	5.49	0.13/−0.01
R Crus II*	Temporal Pole	L	21	42	6	−30	54	6.14	0.14/−0.11
L Lobule VIIb*	Temporal Pole	R		30	−36	−48	426	5.48	−0.12/−0.37
	Lobule VIII/X	R		−24	−84	−48	248	5.93	−0.19/−0.62
R Lobule VIIb*	Lobule VIII	L		−21	−78	−51	462	5.11	−0.61/−0.90
	Lobule IX	L		9	−69	−48	569	4.99	−0.34/−0.76
	Lobule VIII/IX	R	38	−30	−3	−51	131	5.56	0.01/−0.15
	Superior Temporal Gyrus	L	38	27	0	−54	43	4.50	0.01/−0.04

^* p<0.05 (False Discovery Rate corrected) with cluster size >10 voxels. ** p<0.001 (uncorrected) with cluster size >50 voxels. L: left; R: right; FDR: False Discovery Rate; MDD: Major depressive disorder; HC: Healthy control.