Figure 8. NaPB protects dopaminergic neurons in MPTP-intoxicated mice.

Mice receiving NaPB (200 mg/kg body wt/day) from 3 h after the last injection of MPTP were sacrificed 7 d after the last injection of MPTP followed by TH immunostaining of SNpc (A) and striatum (B), counting of TH-positive neurons in SNpc (C), quantification of TH-positive fibers in striatum (D), assay of neurotransmitters in striatum (E), and quantification of GSH in nigra (F). Data are means + SEM of eight mice per group. ^ap<0.0001 vs saline group; ^bp<0.0001 vs the MPTP group.