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. 2012 Jun 18;7(6):e38113. doi: 10.1371/journal.pone.0038113

Table 1. Attenuation of proinflammatory cytokine production by NaPB in primary mouse microglia.

Cytokine (ng/mgprotein/24 h) Treatment
Control LPS LPS+NaPB (0.1 mM) LPS+NaPB (0.2 mM) LPS+NaPB (0.5 mM) NaPB (0.5 mM) only
TNF-α 0 18.4+3.1 16.8+1.5 12.7+0.8 8.6+1.1a 0
IL-1β 0 11.2+2.9 9.9+1.4 7.5+1.1 5.3+0.6a 0

Primary microglia preincubated with different concentrations of NaPB for 6 h were stimulated with LPS for 24 h followed by quantification of TNF-α and IL-1β in supernatants by ELISA. Results are mean + SD of three independent experiments.

a

p<0.001 vs LPS.