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. 2012 Jun 18;7(6):e38962. doi: 10.1371/journal.pone.0038962

Table 3. The BD/TDD ratio and insulin dose per kilogram of body weight were then analyzed by stratifying the study subject with age, DM duration, BMI, HbA1c, C peptide level, fasting and 2h glucose level on admission and discharged from hospital, and usage of metformin.

Variables BD/TDD ratio insulin doses perkilogram of body weight Total insulin doseper day
Age* ≤53 years 0.24±0.09 0.57±0.21 38.96±14.25
54–66 years 0.23±0.08 0.59±0.23 39.75±16.14
≥67 years 0.21±0.08 0.57±0.22 35.90±14.04
DM duration ≤7years 0.22±0.08 0.53±0.21 35.60±13.63
8–14years 0.23±0.09 0.58±0.22 38.87±14.80
≥15years 0.23±0.09 0.62±0.23 40.30±15.88
BMI* <22.2 kg/m2 0.21±0.09 0.63±0.23 34.41±12.33
22.2–25.8 kg/m2 0.22±0.08 0.56±0.21 36.89±13.66
≥25.9 kg/m2 0.24±0.09 0.56±0.22 43.40±16.99
HbA1c ≤8.2% 0.22±0.09 0.52±0.20 34.65±13.99
8.3–10.1% 0.23±0.08 0.60±0.24 40.66±16.14
≥10.2% 0.24±0.08 0.62±0.21 39.98±13.61
fasting C-peptide <1.18 ng/dl 0.23±0.08 0.59±0.21 37.42±12.54
1.18–2.04 ng/dl 0.23±0.08 0.59±0.21 40.32±15.23
≥2.05 ng/dl 0.22±0.08 0.58±0.23 40.98±16.30
Postprandial C-peptide <1.89 ng/dl 0.24±0.08 0.62±0.21 38.42±12.91
1.89–3.48 0.24±0.08 0.61±0.22 41.84±15.13
≥3.49 0.22±0.07 0.55±0.22 38.87±15.84
FBG (mmol/L) when admission * <6.95 0.21±0.08 0.53±0.20 35.26±14.07
6.95–9.39 0.23±0.08 0.59±0.22 39.39±14.41
≥9.4 0.25±0.08 0.64±0.23 42.66±15.15
2 hrPBG (mmol/L) when admission * <11.1 0.22±0.09 0.54±0.20 35.98±13.69
11.1–15 0.23±0.09 0.59±0.23 39.97±16.10
≥15.1 0.24±0.08 0.63±0.22 41.34±14.43
FBG (mmol/L) Discharged from hospital <6.4 0.22±0.08 0.55±0.21 36.12±13.18
6.4–7.5 0.22±0.08 0.51±0.21 38.51±14.32
≥7.6 0.24±0.09 0.62±0.24 40.55±16.53
2 hrPBG (mmol/L) Discharged from hospital * <7.8 0.24±0.08 0.58±0.22 37.80±14.03
7.8–9.2 0.22±0.08 0.57±0.22 38.11±14.02
≥9.3 0.21±0.08 0.59±0.23 39.43±15.78
Usage of metformin* Insulin alone 0.22±0.09 0.57±0.23 35.44±14.27
Insulin+metformin 0.24±0.08 0.59±0.22 40.51±15.06
Creatinine (umol/L) <66 0.24±0.08 0.61±0.22 40.13±15.32
66–83 0.23±0.08 0.58±0.22 38.58±14.63
≥84 0.22±0.07 0.54±0.22 37.12±14.86
*

P values among the three groups were less than 0.05.