Table 4. Brain magnetic resonance imaging (MRI) characteristics of study subjects.
| Area of Hyperintensity | Non-Hispanic Whites | Non-Hispanic Blacks | Hispanic Whites | Other | Total |
| (n = 95) | (n = 5) | (n = 6) | (n = 4) | (n = 110) | |
| Mean # of brain MRI’s (SD) | 1.8 (0.75) | 1.5 (1) | 1.5 (0.54) | 1.75 (0.5) | 1.75 (0.74) |
| Median time from onset to initial MRI (S.E), wksa | 10 (1.96) | 13 (3.46) | 17 (6.12) | 5 (4.5) | 11 (1.69) |
| Basal ganglia (%) | 44 (46)b | 4 (80) | 5 (83) | 3 (75) | 56 (51) |
| Thalamus (%)c | 15 (16) | 1 (20) | 1 (17) | 2 (50) | 19 (17) |
| Meets cortical criteria (%)d | 29 (31) | 1 (20) | 2 (33) | 2 (50) | 34 (31) |
| Meets Brain MRI Criteria for sCJD (%)e | 57 (60) | 4 (80) | 6 (100) | 3 (75) | 70 (64) |
Brain MRI was not done for 2 subjects and results were unknown in 4 subjects.
a
imes could not be calculated for 7 subjects.
b
p<0.05.
c
13/15 cases also had basal ganglia hyperintensity.
d
Hyperintensity on DWI/FLAIR in 2 or more cortical areas (temporal, parietal, or occipital lobes) [15].
e
High signal abnormalities in caudate nucleus and putamen or at least two cortical regions (temporal-parietal-occipital) either in DWI or FLAIR [15].