Table 3. Results of the sensitivity analyses: a comparison of different nominal p-values.
Nominal p-value | p (Netherlands) | p (GAIN) | p (Germany) | Fisher’s combined probability test |
.05 | 0.001 | 0.023 | 0.001 | 3.98 E-6 |
0.01 | 0.002 | 0.04 | 0.06 | 4.2 E-4 |
0.1 | 0.001 | 0.001 | 0.003 | 6.4 E-7 |
EIGENSTRAT | 0.004 | 0.001 | 0.04 | 2.23 E-5 |
Note. Results for variations of the method for the 32 Mbp width region on chromosome 5, 128–160 bp. Nom 0.01: the analysis was performed using p = 0.01 as the cutoff for nominal SNP-wise significance. Nom 0.11: the analysis was performed using p = 0.1 as the cutoff for nominal SNP-wise significance. EIGENSTRAT: the analysis was performed on data corrected for population stratification using the EIGENSTRAT procedure.